Full Metal Alchemist; Brotherhood
We just finished Full Metal Alchemist: Brotherhood last night. It's five seasons (64 episodes) of a beautiful story. Author Hiromu Arakawa tells an epic tale of love, family, sacrifice, honor, friendship, morality, war, pain, death, tragedy and hope. Her characters are complex, the story is subtle and has many layers and is delightfully unpredictable. Considering how much media I've consumed over the decades, that's high praise indeed.
It's amazing how much I've come to love these characters - but they're easy to love. :)
I know there are a lot of people that don't 'get' anime, or somehow are under the assumption that it's a child's story because it's animated. (I know a lot of you will say "that's not true anymore" but while the Internet has allowed you to more easily find people with your own interests, I'm sorry to say that the wide world still looks a bit askance at anime.) I would argue that this story, with is broad and wonderful appeal, is a good way to introduce someone to anime.
If you're curious and have been wondering what it's all about - Full Metal Alchemist: Brotherhood is a great place to start.